MicroRNA and Cardiovascular Disease 2016
نویسندگان
چکیده
1Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University, Changsha 410011, China 2Division of Pulmonary and Critical Care Medicine, Stanford University Medical Center, Stanford, CA 94305, USA 3Departments of Cardiothoracic Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China 4Warsaw University of Life Sciences, 02-787 Warsaw, Poland 5Chang Gung Memorial Hospital, Keelung 20445, Taiwan
منابع مشابه
The Emerging Role of MicroRNA-155 in Cardiovascular Diseases
MicroRNAs have been demonstrated to be involved in human diseases, including cardiovascular diseases. Growing evidences suggest that microRNA-155, a typical multifunctional microRNA, plays a crucial role in hematopoietic lineage differentiation, immunity, inflammation, viral infections, and vascular remodeling, which is linked to cardiovascular diseases such as coronary artery disease, abdomina...
متن کاملInvolvement of microRNA-133 and -29 in cardiac disturbances in diabetic ovariectomized rats
Objective(s): Menopause and diabetes obviously increase the risk of cardiovascular disease in women. The aims of the present study were to evaluate the effects of ovariectomy in type 2 diabetes on the histology and expression of miRNA-29, miRNA-133, IGF-1 and Bcl-2 genes and Bcl-2 protein and caspase 3 activity in the hearts of female rats. Materials and Methods: Forty Female Wistar rats were ...
متن کاملCancer virotherapy: Targeting cancer cells by microRNA mechanism for selective replication of oncolytic viruses in these cells
Cancer, as one of the most serious public health problems, is the second-leading cause of death in the world after cardiovascular disease. The number of patients and the resulting mortality are increasing worldwide; therefore, early diagnosis, prevention, and effective treatment of cancer are very important. Current treatments such as chemotherapy and radiation therapy are often non-selective a...
متن کاملEvaluation of Extracellular Circulating Human MicroRNA-197 as a Target Biomarker in Patients with Coronary Artery Disease
Background: Coronary Artery Disease (CAD) refers to the reduction or blockage of all or part of the coronary arteries due to the process of atherosclerosis or the presence of a clot. The aim of this study was to investigate the association of serum miR-197 as a diagnostic index in patients with coronary artery disease. Methods: In this study, 100 patients with CAD were selected. Extraction of...
متن کاملTargeting microRNAs in heart failure.
MicroRNAs play pivotal roles in cardiac disease, and their therapeutic modulation raises exciting and unique opportunities, as well as challenges in the path toward clinical development and implementation. In this review, we provide a detailed overview of recent studies highlighting the important role of microRNAs in heart failure (HF) and the potential use of microRNA-based technology for diag...
متن کاملRacial differences in microRNA and gene expression in hypertensive women
Systemic arterial hypertension is an important cause of cardiovascular disease morbidity and mortality. African Americans are disproportionately affected by hypertension, in fact the incidence, prevalence, and severity of hypertension is highest among African American (AA) women. Previous data suggests that differential gene expression influences individual susceptibility to selected diseases a...
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عنوان ژورنال:
دوره 2017 شماره
صفحات -
تاریخ انتشار 2017